Membrane Trafficking and Development of Plants
Exploring Plant-Environment Interactions and Root Behavior
After completing his studies in Taiwan, Wei pursued his PhD at the University of Bonn in Germany, focusing on synaptotagmin 1 (SYT1) and VAP27-1 at ER-PM contact sites in Arabidopsis. He returned to Taiwan for his first postdoc at Academia Sinica in Paul Verslues' lab, where he investigated drought signaling of various cytoskeleton- and vesicle-associated proteins. Wei then moved to Belgium to join Jenny Russinova at the VIB, where he built the protein interactome of adaptor protein complexes involved in endocytosis. Later, he joined Marco Trujillo's team at RWTH Aachen in Germany, developing strategies for targeted protein degradation (TPD) in plants. In 2024, Wei became an assistant professor at NTU, leading research on plant root behavior, stress responses and intracellular trafficking.
Kai-Chun Peng obtained his Ph.D. from the Institute of Plant Biology at National Taiwan University, where he focused on studying the interaction between phyB-mediated photophysiology and FIN219-mediated defense responses in Hsieh Hsu-Liang's laboratory. Currently, in Wei Siao‘s group, his research is focused on intracellular membrane trafficking. By tracking the molecules' migration between different organelles and analyzing their distribution on membranes, he investigates how membrane molecule dynamics influence root morphology development and mechanosensing in plants.
Tze-Ching Chan obtained his Master’s degree from the Department of Horticulture and Landscape Architecture at National Taiwan University. During the Master’s program, he analyzed RNA-seq data from two cabbage cultivars with different flooding tolerances to identify differentially expressed genes (DEGs) associated with flooding tolerance in cabbage. He also established a transient gene expression system using cabbage protoplasts under hypoxia-mimicking conditions to search for marker genes related to flooding tolerance. After graduation, he joined Dr. Ho-Ming Chen’s laboratory at Academia Sinica as a research assistant for two years, where he participated in studies on nonsense-mediated decay as well as bioinformatics research. He is currently pursuing his Ph.D. in Dr. Wei Siao’s laboratory, focusing on the relationship between retromer proteins and endocytosis in plant cells, and investigating how phosphorylation of plant plasma membrane proteins is recognized and subsequently leads to endocytosis, thereby influencing plant physiological processes.
Pei-Shan Shen obtained a master's degree in the Department of Biological Sciences at National Sun Yat-sen University. In the past, her research focused on the behavior of wild animals. After graduation, she founded "Kids of Forest Studio," dedicated to exploring the wonders of nature with preschool children and their families. Currently, she is also part of Wei Siao's research team, mainly assisting with administrative, financial, and other general management tasks.
Hsiang Lin graduated from the Department of Life Science at National Taiwan University. As an undergraduate, he conducted research on molecular biology in cyanobacteria in Professor Ming-Yang Ho's lab. Driven by his interest in plant cell biology, he joined Siao's lab for his master's studies to investigate the roles of various molecules involved in plant endocytosis and their regulation of plant growth and development.
Tzu-Chen Yang graduated from Department of Life Sciences, National Cheng Kung University. As an undergraduate in Dr. Hong-Hwa Chen’s lab, she studied the mechanism of PeMYBx for anthocyanin accumulation in the purple region of harlequin Phalaenopsis flowers. She joined the Siao lab for her master's studies to investigate how plant cells regulate root development, hydrotropism, mechanosensing and stress responses through the ER-PM contact sites, membrane vesicle trafficking and endocytosis.
Ken Chen Graduated from the Bio-Tech department of National Chiao Tung University. During university, he joined Professor Yu Chung-Su’s Lab and carried out research into producing bi-functional antibody drug using E.coli. Due to his interest in plant cell endocytosis, he joined Professor Wei Siao’s lab, hoping to dive more deeply into the topic of plant endocytosis mechanisms and how different signal molecules can regulate plant growth and development.
Yi-Hsuan Huang graduated from the Department of Agronomy at National Chung Hsing University.Conducted research in Dr. Hsin-Hung Lin's laboratory exploring the physiological effects of ultraviolet radiation on cyanobacteria and their symbiotic mechanisms with rice. Driven by an interest in plant cell biology,I joined Dr. Wei Hsiao's laboratory for their master's studies to investigate adaptor proteins that recognize phosphorylated and ubiquitinated cargoes. This research examines how these proteins control endomembrane system trafficking mechanisms—such as endocytosis and vesicle transport—thereby influencing behaviors like root growth, development, and gravitropism.
Guo Zhi-Yun graduated from the Department of Biotechnology at National Kaohsiung Normal University (NKNU). During her undergraduate studies, she worked in Dr. Chen Yu-Chi's laboratory, researching the use of prodigiosin to prevent bacterial wilt and late blight in tomatoes, which sparked her keen interest in plant cell biology. For her master's degree, she joined Dr. Hsiao Wei's laboratory to explore how organelle interactions during plant endocytosis exert mechanistic impacts and regulate plant growth and development.
Pei-Ru Chen graduated from the Department of Life Sciences, National Central University. As an undergraduate, she investigated candidate interaction partners of small heat shock protein 16.9A in Prof. Ching-Hui Yeh’s lab. She joined Siao’s lab and conducted research under the co-supervision of Prof. Siao and Prof. Jinn to study how endocytosis and vesicle trafficking affect root tropism during development.
Shuo-Yu Liang is a bachelor student in the Department of Agronomy at National Taiwan University. Driven by a deep curiosity about the applications of molecular biotechnology, he joined Wei Siao’s lab for research training. Through hands-on experiments and research discussions, he has gained an in-depth understanding of molecular mechanisms in plant cells and has further explored how these technologies and insights can be applied to the improvement and cultivation of agricultural crops.